The multicenter trial was called Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care, or EMBARC. The paper is one of several based on data from a federally funded depression study launched in 2011 - the largest randomized, placebo-controlled clinical trial on antidepressants ever conducted with brain imaging - which tested the use of sertraline in 309 medication-free patients. Wei Wu, PhD, an instructor of psychiatry at Stanford, is the lead author. Instead of functional magnetic resonance imaging, an expensive technology often used in studies to image brain activity, the scientists turned to electroencephalography, or EEG, a much less costly technology.Įtkin shares senior authorship of the paper with Madhukar Trivedi, MD, professor of psychiatry at the University of Texas-Southwestern. “I will be surprised if this isn’t used by clinicians within the next five years.” “This study takes previous research showing that we can predict who benefits from an antidepressant and actually brings it to the point of practical utility,” said Amit Etkin, MD, PhD, professor of psychiatry and behavioral sciences at Stanford. Currently, there are no such tests to objectively diagnose depression or guide its treatment.
The study emerged from a decades-long effort funded by the National Institute of Mental Health to create biologically based approaches, such as blood tests and brain imaging, to help personalize the treatment of depression and other mental disorders. Stanford researchers and their collaborators used electroencephalography, a tool for monitoring electrical activity in the brain, and an algorithm to identify a brain-wave signature in individuals with depression who will most likely respond to sertraline, an antidepressant marketed as Zoloft.Ī paper describing the work was published today in Nature Biotechnology. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.A new method of interpreting brain activity could potentially be used in clinics to help determine the best treatment options for depression, according to a study led by researchers at the Stanford School of Medicine. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file.
#Brain wave analyzer software#
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Now, I need your help to get back to the year 1985.ĭoc: My God! Do you know what this means ? It means that this damn thing doesn't work at all! I came here in a time machine that you invented. You come here from a great distance?ĭoc: Don't tell me! You want me to subscribe to the "Saturday Evening Post".ĭoc: Not a word now! Quiet. I want to know nothing about you.ĭoc: Quiet. English: Cosplay of Doctor Emmett "Doc" Brown with the brain-wave analyzer, an invention that appears in a scene of the 1985 film Back to the Future.ĭoc: Don't say a word.
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